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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOS2
All Species:
16.67
Human Site:
T1193
Identified Species:
36.67
UniProt:
Q07890
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07890
NP_008870.2
1332
152979
T1193
K
P
R
V
P
V
P
T
G
A
F
D
G
P
L
Chimpanzee
Pan troglodytes
XP_515425
1598
179688
S1462
K
A
Y
S
P
R
Y
S
L
S
D
R
T
S
I
Rhesus Macaque
Macaca mulatta
XP_001099864
1331
152695
T1193
K
P
R
V
P
V
P
T
G
A
F
D
G
P
L
Dog
Lupus familis
XP_547804
1363
156214
T1224
K
P
R
V
P
A
P
T
G
A
F
D
G
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q02384
1333
153108
M1194
K
P
R
V
P
V
L
M
G
T
F
D
G
P
V
Rat
Rattus norvegicus
NP_001129033
1333
153157
T1194
K
P
R
A
P
V
L
T
G
T
F
E
G
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515100
1332
152934
G1193
K
P
R
V
P
A
Y
G
G
P
F
E
G
P
L
Chicken
Gallus gallus
XP_421461
1466
167231
Y1327
I
Q
P
R
A
P
A
Y
S
P
F
E
Q
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690171
1343
153249
N1189
Q
P
R
V
P
V
I
N
G
P
T
D
G
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26675
1596
177916
T1335
H
V
N
V
P
M
A
T
N
M
E
Y
R
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782335
1310
150821
P1188
P
P
R
T
Y
R
S
P
H
S
H
S
L
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.7
99
93.2
N.A.
94.9
94.6
N.A.
91.1
78.9
N.A.
73
N.A.
39.8
N.A.
N.A.
52.1
Protein Similarity:
100
68.5
99.7
95.5
N.A.
97.9
97.4
N.A.
95.9
84.7
N.A.
83.9
N.A.
55.1
N.A.
N.A.
68
P-Site Identity:
100
13.3
100
93.3
N.A.
73.3
66.6
N.A.
66.6
20
N.A.
66.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
33.3
100
93.3
N.A.
80
80
N.A.
73.3
26.6
N.A.
73.3
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
19
19
0
0
28
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
46
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
28
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
64
0
0
0
64
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
19
0
10
0
0
0
10
0
55
% L
% Met:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
73
10
0
82
10
28
10
0
28
0
0
0
73
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
0
0
73
10
0
19
0
0
0
0
0
10
10
0
10
% R
% Ser:
0
0
0
10
0
0
10
10
10
19
0
10
0
10
0
% S
% Thr:
0
0
0
10
0
0
0
46
0
19
10
0
10
0
0
% T
% Val:
0
10
0
64
0
46
0
0
0
0
0
0
0
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
19
10
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _